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Vernonia amygdalina | |
---|---|
Scientific classification | |
Kingdom: | Plantae |
(unranked): | Angiosperms |
(unranked): | Eudicots |
(unranked): | Asterids |
Order: | Asterales |
Family: | Asteraceae |
Genus: | Vernonia |
Species: | V. amygdalina |
Binomial name | |
Vernonia amygdalina Delile |
Vernonia amygdalina extracts may help suppress, delay, or kill cancerous cell in many ways, such as:
- Induction of apoptosis as determined in cell culture and animal studies.[2][3]
- Enhanced Chemotherapy Sensitivity - V. amygdalina extracts may render cancerous cells to be more sensitive to chemotherapy.[2]
- Inhibition of the growth or growth signals of cancerous cells.[4][5][6][7]
- Suppression of metastasis of cancerous cells in the body by the inhibition of NFҡB is an anti-apoptotic transcription factors as demonstrated in animal studies.[3]
- Reduction of estrogen level in the body by the suppression of Aromatase activity.[8] The Involvement of blood estrogen level in the etiology of estrogen receptor (ER) positive breast cancer has been widely reported.[9] Additional source of estrogen production in humans besides the ovary and adrenal gland is the conversion of testosterone to estrogen in a reaction catalyzed by Aromatase. Many studies have shown positive correlations between blood estrogen levels and breast cancer risks.[9] Therefore, compounds that inhibit Aromatase activity are used for the treatment of breast cancer.
- Antioxidants - V. amygdalina may provide anti-oxidant benefits.[10]
- Enhancement of the immune system - Many studies have shown that V. amygdalina extracts may strengthen the immune system through many cytokines (including NFҡB, pro inflammatory molecule) regulation.[2]
V. amygdalina, traditionally used by small farmers in Western Africa, does possess anthelminthic anti-parasitic properties.[12]
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